University of California at San Diego biochemists have developed a computer program that helps explain how the same proteins can play different roles in a wide range of cellular processes.
University of California at San Diego biochemists have developed a computer program that helps explain how the same proteins can play different roles in a wide range of cellular processes, including those leading to immune responses and cancer. Researchers report that their computer model accurately predicts particular behaviors of living cells.
"Our computational approach revealed how the same set of proteins produce physiologically different outputs in response to only subtly different inputs," explained Alexander Hoffmann, an assistant professor of chemistry and biochemistry, who led the team.
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