Zuckerberg, who dropped out of Harvard to run Facebook, is a shy programmer turned billionaire with an anything-but-humble vision to make the world a more "transparent" place to live.
Facebook, which encourages members daily to share text and photos, videos, music or other personal information with others in their network, has been translated, largely by its own users, from English into 20 languages since the start of 2008.
Zuckerberg, who grew up in an affluent suburb north of New York City, described the epiphany he had last year while traveling in Istanbul. "A couple of bloggers called it my vision quest, but I called it a vacation," he joked.
Free of his Blackberry and daily management pressures, Zuckerberg said he got to define some ambitious new goals.
"I want to be able to build a product that allows you to be able to see a person and feel their presence, to have people have more open connections by helping them to share more," he told attendees at the event in San Francisco on Wednesday.
"Facebook's mission ... is to give people the power to share (information) in order to make the world more open and connected. By giving people the power to share, it makes it more transparent," Zuckerberg told the audience.